Artificial sugars could trick the reward system of your brain. Eating real sugar releases dopamine in the reward area of your brain, which contributes to the delicious taste you experience. At the same time, the leptin hormone, which regulates the appetite, triggers a feeling of satiety and reduces the flow of dopamine to your brain.
This balanced system prevents you from eating too much, because the more you eat, the more you have a feeling of fullness, and the less the food becomes pleasant. But regularly eating artificial sweeteners alters your brain’s reward system, because the taste of sweetness ceases to be a reliable measure of caloric intake.
While research is only beginning to discover how this alteration impacts health in the long run, this suggests that the key would be to moderate the consumption of true and false sugar.